MIRROR - Photobiomodulation Research Portfolio to Enhance Military Readiness- MHSRS 2024

Metzger e, hager n, ory r, lucio w, mckee s, anders j, givens m, wagner l, isaacson b, pasquina p

Abstract accepted for Oral presentation at the 2024 Military Health System Research Symposium

Photobiomodulation (PBM) involves applying non- ionizing forms of light from various sources including lasers, light-emitting diodes (LEDs), and broadband light, in the visible and near infrared spectrum, to biologically modulate cellular activity to enhance healing. PBM treatment can enhance repair and regeneration of tissue, stimulate metabolism, and reduce inflammation and pain during injury recovery. We are investigating use of this modality to increase Warfighter quality of life, and improve operational readiness, focusing on musculoskeletal (MSK) injury, performance, recovery, self-reported behavioral health, wellness, and nerve, hearing, and wound healing.

The Defense Health Agency supported the creation of the Photomedicine to Enhance Military Readiness program. This portfolio utilizes 16 PBM studies - 7 basic science studies, 8 randomized-control clinical trials, 1 normative study - to assess and