Eliason A, Weart A, Miller E, Reilly N, Haltiwanger H, Gonnella M, Crowell M, Goss D

Abstract submitted to American College of Sports Medicine Annual Meeting & World Congresses 2023

Despite the inherently dangerous nature of combat, the most prevalent cause of injury observed in military servicemembers (MSMs) stems from running, possibly due to the large cumulative mechanical stresses incurred. Running-related injuries in the military have primarily been addressed by in-person rehabilitation, but limitations exist inequipment and clinician availability. Recently, telehealth has emerged as a method to reach and provide rehabilitative care to a greater number of patients as well as populations without ready access to laboratory-grade assessment tools. However, applications of telehealth for targeting biomechanical parameters associated with running-related injury in the armed services to improve clinical outcomes have not been explored. The purpose is to evaluate the viability of telehealth gait retraining as a modality to identify and modify gait-related kinetic parameters conducive to running-related injury risk in MSMs.

Yang K, Weart A, Miller E, Reilly N, Crowell M, Ford K, Mulier L, Goss D

Abstract submitted to American College of Sports Medicine Annual Meeting & World Congresses 2023

Running is the primary cause of musculoskeletal injury and lost or limited duty days in military service members (MSMs). Telehealth gait retraining is an accessible healthcare intervention showing promise in altering foot strike patterns that influences kinetic and spatiotemporal parameters, reducing mechanical strain and potentially reducing injury risk. However, it is inconclusive whether biomechanical changes resulting from telehealth gait retraining persist after the intervention is completed. The purpose is to determine the long-term efficacy of an 8-week telehealth gait retraining program to target and modify gait-related kinematic parameters.

Reilly N, Miller E, Weart A, Haltiwanger H, McHenry P, Ford K, Crowell M, Goss D

Abstract submitted to American College of Sports Medicine Annual Meeting & World Congresses 2023

Running is the most common mechanism of injury in the military service member (MSM) population. Specifically, cumulative stresses incurred using suboptimal kinematic patterns continuously predispose MSMs to increased risks of running-related injury. The gold-standard laboratory-grade equipment and time requirements necessary for biomechanical analyses of gait are unavailable for the MSM population. Recently, the advent of telehealth has diversified options and access to clinical treatment for a variety of pathologies. However, the effectiveness of telehealth to address risk factors contributing to running-related injury for MSMs is, to date, largely unexplored. The purpose is to evaluate the efficacy of telehealth gait retraining in addressing kinematic risk factors associated with running-related musculoskeletal injury in military personnel.

Goss D, Ignacio G, Helton M, Gonnella M, Reilly N, Haltiwanger, Yang K, Gailey

Abstract submitted to American College of Sports Medicine Annual Meeting & World Congresses 2023

Musculoskeletal injuries (MSI) affect approximately 800,000 service members and 25 million days of limited duty annually. There is a need for quick screening assessments that can classify and predict the risk of lower extremity (LE) MSI prior to activity. An Injury Risk Index (IRI) could facilitate improved decision-making and reduce the negative impact associated with selected MSI. The purpose of this study is to determine the frequency and distribution of Soldiers’ risk of MSI injury after performing sensors-based objective LE tests for static and dynamic stability. As of December 2022, 263 (92% male, 8% female) United States Army Soldiers were recruited, and provided demographic and previous joint-specific injury history information. Soldiers donned a sleeve with two inertial measurement unit sensors over each knee. They performed single limb stance (SLS) tests to obtain Region of Limb Stability (ROLS) values, which measures static LE stability. A four-meter sidestep test (FmSST) was used to obtain the Transitional Angular Displacement of Segments (TADS) values as a metric of dynamic joint stability. The ROLS and TADS symmetry values between LEs is calculated for both tests and the values are used to determine IRI category as low, moderate, or high risk for injury. [RN1] Total assessment time was < 15 minutes per Soldier. Descriptive statistics and frequency distributions were used to characterize the study population.

Crowell M, Pitt W, Mason J, Posner M, Cameron K, and Goss D

Abstract selected for a podium presentation at 2023 American Physical Therapy Association Combined Sections Meeting in San Diego, California

Shoulder instability is common in active young athletes and military personnel, often requiring shoulder stabilization surgery. Acute post-operative pain is usually managed with opioid pain medications, which have adverse effects that reduce military readiness. Battlefield Acupuncture (BFA) has demonstrated promise as a non-pharmaceutical intervention for acute post-operative pain. The purpose of this randomized clinical trial was to assess the effectiveness of BFA on post-surgical pain and opioid medication usage.

Symsack A, Haynes J, Gaunaurd I, Clemens S, Gruenhagen Lucarevic J, Bennet C, Isaacson B, Pasquina P, Gailey R

Abstract selected for a podium presentation at 2023 American Physical Therapy Association Combined Sections Meeting in San Diego, California

Veterans with lower limb loss (LLL) face many challenges (time and cost) to receive appropriate prosthetic training and exercises that could improve their gait quality and functional mobility. The VA and DoD supported the development of the Mobile Device Outcomes-based Rehabilitation Program (MDORP). MDORP is a comprehensive mobile rehabilitation program that includes a wearable sensor system called the Rehabilitative Lower Limb Orthopedic Assistive Device (ReLOAD). The ReLOAD system assesses gait and provides real-time audio feedback during home walks to correct specific gait deviations and subsequently recommend targeted exercises. The purpose of this study was to examine the changes in mobility, gait quality, and strength for lower functioning Veterans with LLL after completing the 8-week MDOR Pprogram

Miller E, mason J, Pitt w, Crowell M, Wear A, Reilly N, Haltiwanger H, Gonnella M, Goss D

Abstract selected for a podium presentation at 2023 American Physical Therapy Association Combined Sections Meeting 2023 in San Diego, California

Previous research has identified numerous biomechanical variables that may relate to musculoskeletal injury risk. Gait retraining interventions have successfully altered running biomechanical risk factors for overuse knee injury in non-military populations. However, constraints on patient time and frequency of in-clinic visits limits implementation of gait retraining interventions in the Military Health System (MHS). The purpose of this randomized clinical trial was to determine the effect of a telehealth gait retraining intervention on the running kinematics in patients with an overuse knee injury.

RHON D, TEYHEN D, COLLINS G, BULLOCK G

Abstract submitted to The World Congress of Sports Physical Therapy 2022

Using the same data, compare performance between an injury prediction model categorizing predictors and one that did not, and compare selection of predictors based on univariate significance versus assessing non-linear relationships. Validation and replication of a previously developed injury prediction model in a cohort of 1466 healthy military service members followed for one year after physical performance, medical history, and sociodemographic variables were collected. The original model dichotomized 8 predictors. The second model (M2) kept predictors continuous but assumed linearity, the third model (M3) conducted non-linear transformations. The fourth model (M4) chose predictors the proper way (clinical reasoning and supporting evidence) which led to an addition of 7 additional predictors (15 predictors total), but still kept predictors dichotomized. Model performance was assessed with R2, calibration in the large, calibration slope, and discrimination. Decision curve analyses were performed with risk thresholds from 0.25 to 0.50.

Persinger J and Hager N

Abstract submitted to American Institute of Ultrasound in Medicine 2022

The Physical Medicine and Rehabilitation Clinic (PM&R) at Walter Reed National Military Medical Center (WRNMMC) augmented their high frequency ultra-sound systems with an ultra-high frequency ultrasound (UHFUS) system for use in the diagnosing and treatment of musculoskeletal (MSK) and nerve injury warfighters. The Visualsonics VevoMD is an UHFUS system with operating frequencies in the 24–70 MHz range as compared to the typical POC and tertiary care ultrasound systems operating in the15–22 MHz range. Access to this system afforded a unique opportunity to explore the usefulness of this cutting-edge technology in the unique settings of limb loss and multi-trauma in the military.

Super E, Smith M, Persinger J, Hager N, Smith J, Miller M, Yuan X

Abstract Submitted to WRNMMC Research and Innovation Month 2022

Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment. Interventional procedures for CTS include carpal tunnel (CT) injections and CT release (CTR). Variant anatomy increases the risk of iatrogenic injury and complications, impairing recovery and leading to post-procedural functional deficits. The objective of this study was to evaluate anatomic variations associated with CTS or at risk of injury during procedures using high-frequency ultrasound (HFUS). In this cross-sectional, observational study of 100 eligible patients (age: 44.4 ± 13.0 years, 37.0% female) referred for upper extremity (UE) electrodiagnostic studies (EDX), the MN was systematically evaluated using high-frequency ultrasound (HFUS) from the elbow to the CT outlet. The presence/absence of Martin-Gruber anastomosis (MGA), palmaris longus, and lumbrical intrusion with dynamic finger flexion at the CT inlet were documented, along with the course of the palmar cutaneous branch of the MN (PCBMN) and thenar motor branch (TMB. The cross-sectional area (CSA) of the MN at the level of the CT inlet and the transverse safe zone (TSZ) for CTR were measured. Statistical analyses were conducted using GraphPad Prism. All data are presented as mean ± standard deviation or percentage (%).

Smith M, Bradley M, Kasuske A, Smith J, Nanos G, Tintle S, Reece D, Yuan X, Miller M

Submitted to WRNMMC Research and Innovation Month 2022

Within the Military Healthcare System (MHS), endoscopic and mini-open carpal tunnel release (mOCTR) procedures are the current standard of care for management of refractory Carpal Tunnel Syndrome (CTS), the most common peripheral neuropathy. Carpal Tunnel Release using Ultrasound Guidance (CTR-US), which involves a single 4-6 mm incision, is showing potential as a treatment option for eligible candidates within the military population with CTS in an ongoing randomized controlled trial (RCT) at Walter Reed National Military Medical Center (WRNMMC).

Smith M, Huszar M, Pav V, Hando B, Deal J, Yuan X

Abstract submitted to SOMOS 64h Annual Meeting

Carpal Tunnel Syndrome (CTS) is the most common peripheral entrapment neuropathy, impacting the health, performance, and readiness of Active-Duty service members (ADSMs) of the U.S. Military. However, for ADSMs who seek surgical management for severe or refractory CTS with Carpal Tunnel Release (CTR), access to subspecialty providers within direct care (DC) Military Treatment Facilities (MTFs) can be limited, leading to reliance on care outside MTFs within the private sector (PS). It is currently unknown how the COVID-19 pandemic has impacted provision of and access to care for CTS and CTRs across DC and PS. Therefore, the purpose of this study is to describe regional trends and variation in CTRs performed across Defense Health Agency (DHA) markets within the Military Health System (MHS) over Fiscal Years (FY) 2019-2021. All study procedures were approved by the Uniformed Services University’s Institutional Review Board. We queried the MHS Data Repository to identify all ADSMs with outpatient encounters in DC and PS by International Classification of Diseases, Tenth Revision diagnosis codes for CTS, and CTRs by Current Procedural Terminology codes, during FYs 2019-2021. We further classified CTRs by FY, DC vs. PS, DHA markets, and setting [e.g., Ambulatory Surgical Center (ASC), clinic]. PS encounters were derived using per person per day logic and mapped to DHA markets by zip codes within 40 miles of MTF Service Areas.

Gaunaurd I, Gailey R, Symsack A, Isaacson B, Pasquina P

Abstract submitted to 44th ICMM World Congress on Military Medicine 2022

Service Members (SM) and Veterans with lower limb amputation (LLA) are at a high risk for developing secondary co-morbidities such as joint pain, osteoarthritis, chronic low back pain, and cardiovascular disease. To mitigate these secondary comorbidities, optimize long-term function, and increase quality of life, effective rehabilitation and innovative lifelong care is essential. Telerehabilitation has recently demonstrated to be a useful method of healthcare delivery, particularly benefitting individuals with physical limitations who are unable to attend outpatient physical therapy, such as patients following LLA. Wearable technology, such as mobile sensors, has the potential to augment current telerehabilitation practice and improve home walking and exercise compliance for those with LLA. Therefore, could this technology be used to provide “booster” prosthetic training to improve or reinforce current mobility and prosthetic use, promote an active, healthy lifestyles and mitigate adverse secondary comorbidities? To address this question, the Department of Defense (DoD) and Veterans supported the development of a program through the Joint Incentive Fund called the Mobile Device Outcomes-based Rehabilitation Program (MDORP). The MDORP is a comprehensive mobile rehabilitation program that is clinician-guided and incorporates the use of a mobile sensor system called the Rehabilitative Lower Limb Orthopedic Assistive Device (ReLOAD). The ReLOAD system provides: (1) assessment of walking quality at home and in the community for people with LLA, (2) real-time auditory feedback to correct the most prominent gait deviations, and (3) automatic prescription of home exercises that target balance and strength impairments related to their most prominent gait deviation. The primary objective of the study was to determine if the 8-week MDORP improved strength, mobility, and gait quality in SMs and Veterans with LLA.

Pasquina p, Jannace k, Nordstrom m, Gbade-Alabi o, Smolinski g

Selected for a podium presentation at the 44th ICMM World Congress on Military Medicine 2022 in Brussels

Gailey R, Gaunaurd I, Goss D, Bennett C, Isaacson B

Abstract submitted to 44th ICMM World Congress on Military Medicine 2022

Isaacson B, Wagner L, West S, Lucio W, Yuan X, Hager N, Pasquina P

Abstract submitted to Military Health System Research Symposium 2022.

Musculoskeletal injuries (MSI) affect approximately 800,000 Service Members annually and result in 25 million limited duty days. These conditions are the primary reasons for medical discharge and downgrade, and result in 34% of evacuations from theatre. Most concerning is that the disability discharge rate for MSI has increased 13x between 1981 and 2005 (70 vs. 950 per 100,000 persons). The alarming increase of MSI has also been observed in the general population, with an estimated 126.6 million Americans (one in every two adults) affected by a musculoskeletal condition — comparable to the total percentage of Americans living with a chronic lung or heart condition and costing an estimated $213 billion. Given the strict requirements for physical fitness in the military and the impact of MSI on combat readiness, the Musculoskeletal Injury Rehabilitation Research for Operational Readiness (MIRROR) organization was established in 2019 to advance the treatment and preventive care for Service Members with non-combat related MSI. MIRROR coordinates inter-service partnerships with premier academic institutions, primary military treatment facilities (MTFs), and civilian sites that experience a high volume of MSI, but lack a robust infrastructure to conduct rigorous trials. MIRROR is based in the Department of Physical Medicine & Rehabilitation at the Uniformed Services University and closely aligns with the Defense Health Agency (DHA), Department of Defense (DoD) leadership, Joint Program Committee (JPC) chairs, and other high-level advisory groups. In addition, our Steering Committee, comprised of nationally-renowned military and civilian subject matter experts in various musculoskeletal subspecialties, provides guidance and oversight on MIRROR’s direction, scope, and overall methods. The MIRROR organization also incorporates select MSI sub-portfolios (i.e., orthopedics, interventional spine and pain management, physical and occupational therapy), under the direction of subject matter experts, to further advance our mission across all MSI research areas. Our representation across both operational leadership and research subspecialties allows MIRROR to maximize its impact throughout the MHS. To ensure that findings are clinically translational, data is collected using standardized protocol content, case report forms, and recruitment/outcomes captured through REDCap. Real-time feedback is provided using PowerBI to ensure that data can be presented in a highly efficient manger without the risk of protected health information (PHI) disclosure. This allows quick assessment of key performance indicators and provides useful data to understand healthcare disparities.

Greenlee T, Bullock G, Teyhen D, Rhon D

Abstract submitted to Military Health System Research Symposium 2022.

Prevalence and burden of musculoskeletal injuries for military service members are high, with recurrent injuries contributing to greater costs, more time lost from duty, and sub-optimal force readiness. Several psychological factors are associated with injury and return to work readiness in sport and occupational settings. We explored whether the psychological state of soldiers returning to duty following an injury could predict time-loss injury within the next year. We performed a secondary analysis of data from a longitudinal cohort study of soldiers returning to full duty after a recent thoracolumbar spine (TLS) or lower extremity (LE) injury after seeking medical care. A psychological profile (depression, anxiety, anger, fear, frustration, exercise enjoyment, job-, military-, and life-satisfaction, kinesiophobia, fear avoidance beliefs, pain catastrophizing, stress, and mood) was assessed via self-report at the point of initial return-to-duty and Soldiers were followed for one year.

Foster K, Greenlee T, Fraser J, Young J, Rhon D

Abstract submitted to Military Health System Symposium 2022

One in every four individuals with an ankle sprain went on to have a proximal joint injury in the following year, knee and lumbar spine diagnoses occurring more frequently than hip. Associated fracture with the initial ankle sprain increased the odds of sustaining a subsequent hip or lumbar spine injury. Further, females had higher risk of developing subsequent hip or lumbar spine injuries after ankle sprain whereas males were more likely to develop subsequent knee issues. Less than half of the cohort received rehabilitation following an ankle sprain, but exercise therapy was found to be preventative of secondary injuries to the knee, hip, and lumbar spine. While these associations are often discussed by clinicians, the increased understanding of prevalence of proximal joint disorders has the potential to help guide treatment and inform decisions related to returning to work and sport, improving the care for patients and decreasing the physical and financial toll of this common injury.

Smith M, West S, Malanga G, Hager N, Hulsopple C, Yuan X

Abstract submitted to Association of Military Surgeons of the United States 2022

The Musculoskeletal Injury Rehabilitation Research for Operational Readiness (MIRROR) organization, based out of the Department of Physical Medicine and Rehabilitation (PM&R) at the Uniformed Services University (USU), is dedicated to advancing musculoskeletal injury rehabilitative care within the Military Healthcare System (MHS) to reduce the burden of musculoskeletal injuries on operational readiness. Through its core infrastructure and inter-service collaborations, MIRROR facilitates training programs for medical education to expand and optimize treatments. Knee injuries are one of the most common musculoskeletal complaints among Active Duty military personnel. Autologous micro-fragmented adipose tissue (MFAT) has shown promise as a regenerative therapy for meniscal tears in the civilian population. MIRROR supports a randomized controlled trial (RCT) at multiple military treatment facilities (MTFs), with the objective to investigate the safety and efficacy of intrameniscal injection with autologous MFAT for symptomatic meniscal injuries in a military population. With the assistance of a peer-to-peer, two-day training program incorporating didactic cadaveric training and hands-on patient cases, clinicians at three MTFs garnered the procedural skills required to safely administer this novel intervention prior to the launch of this multi-site study.

Smith M, West S, Persinger J, Hager N, Smith J, Miller M, Yuan X, Reece D

Abstract submitted to Association of Military Surgeons of the United States 2022

The COVID-19 pandemic has taken a significant toll on global medical education and research since March 2020, prompting a surge of virtual learning. Like other research entities, the Musculoskeletal Injury Rehabilitation Research for Operational Readiness (MIRROR) organization, based out of the Department of Physical Medicine and Rehabilitation (PM&R) at the Uniformed Services University (USU), was not spared from the pandemic’s impact on research operations and adapted to persevere, despite setbacks. At the heart of the organization’s mission, MIRROR provides clinicians and researchers with the support and infrastructure to advance musculoskeletal injury rehabilitative care by facilitating training programs for medical education. According to the Defense Medical Epidemiology Database, nearly 17,000 Active Duty service members were diagnosed with carpal tunnel syndrome (CTS) in 2016, the most common peripheral entrapment neuropathy. MIRROR currently supports a study at multiple military treatment facilities (MTFs) comparing Ultrasound-Guided Carpal Tunnel Release (USCTR) to the current standard-of-care surgical release with respect to return to duty and clinical outcomes in the military population with CTS. With the aid of an innovative virtual platform, training for this enhanced intervention continued during the pandemic, propelling MIRROR’s mission to advance military medicine.