Gene Expression Analysis Reveals Differences in the Capsular Tissue of Patients with Anterior and Posterior Shoulder Instability— MHSRS 2023

Galvin J, Rooney p, Egan a, say f, Grassbaugh j, Masini b, free k, bastian m, gillette l, colburn z

Abstracted accepted for a poster session at the 2023 Military Health System Research Symposium

The purpose of this study was to compare gene expression differences in the peripheral blood and capsular tissue of young patients with recurrent anterior shoulder instability and those patients with unidirectional posterior shoulder instability.

There are significant gene expression differences in the shoulder capsule of anterior and posterior shoulder instability patients. This transcriptomic data may provide an improved understanding of the pathobiology of various forms of shoulder instability which could lead to future precision medicine approaches to prevent the development of early glenohumeral osteoarthritis.